alvarez mar

María del Mar Álvarez García

Technical Staff


 

Educational Background

  • 2003. Ph D. in Biology. Complutense University of Madrid.a
  • 1997. Degree in Biology. Complutense University of Madrid

 

Research Interests

 

Active Projects

 


PUBLICATIONS

Previous selected publications

2018

Álvarez M, Nevot M, Mendieta J, Martínez MA, Menéndez-Arias L. Amino acid residues in HIV-2 reverse transcriptase that restrict the development of nucleoside analogue resistance through the excision pathway. J. Biol. Chem. (2018). 293(7):2247-2259

2017

Álvarez M, Sebastián-Martín A, García-Marquina G, Menéndez-Arias L. Fidelity of classwide-resistant HIV-2 reverse transcriptase and differential contribution of K65R to the accuracy of HIV-1 and HIV-2 reverse transcriptases. Sci. Rep. (2017) Mar 23,7:44834 doi:10.1038/srep 44834

2016

Menéndez-Arias L, Sebastián-Martín A, Álvarez M. Viral reverse transcriptases. Virus Res. (2016). Dec 30 doi: 10.1016/ j.virusres 2016.12019

2015

Betancor G, Álvarez M, Marcelli B, Andrés C, Martínez MA, Menéndez-Arias L. Effects of HIV-1 reverse transcriptase connection subdomain mutations on polypurine tract removal and initiation of (+)-strand DNA synthesis. Nucleic Acids Res. (2015) 43(4): 2259-2270

2014

Pauls, E., Ruiz, A., Badia, R., Permanyer, M., Gubern, A., Riveira-Muñoz, E., Torres-Torrenteras, J., Alvarez, M., Mothe, B., Brander, C., Crespo, M., Menéndez-Arias, L., Clotet, B., Keppler, OT., Marti, R., Posas, F., Ballana, E., Esté, JA. Cell cycle control and HIV-1 susceptability are linked by CDK6-dependent CDK2 phosphoriylation of SAMHD1 in myeloid and lymphoid cells. J. Immunol. (2014) 193: 1988-1997

Menéndez-Arias, L., Álvarez, M., Pacheco, B. Nucleside/nucleotide analog inhibitors of hepatitis B virus polymerase: mechanism of action and resistance. Curr Opin Virol. (2014) 8: 1-9

Menéndez-Arias, L., Alvarez, M. Antiretroviral therapy and drug resistance in human immunodeficiency virus type 2 infection. Antiviral Res. (2014) 102: 70-86

Álvarez, M., Menéndez-Arias, L. Temperature effects on the fidelity of a thermostable HIV-1 reverse transcriptase. FEBS J. (2014) 281(1): 342-351

2013

Álvarez, M., Barrioluengo, V., Afonso-Lehmann, RN., Menéndez-Arias, L. Altered error specificity of RNase H-deficient HIV-1 reverse transcriptases during DNA-dependent DNA synthesis. Nucleic Acids Res. (2013) 41(8): 4601-4612

2011

Barrioluengo, V., Alvarez, M., Barbieri, D., Menéndez-Arias, L. Thermostable HIV-1 group O reverse transcriptase variants with the same fidelity as murine leukaemia virus reverse transcriptase. Biochem J. (2011) 436(3): 599-607

2010

Sanz, C., Vazquez ,P., Blazquez, C., Barrio, P., Alvarez, MD., Blazquez, E. Signalling and biological effects of glucagon-like peptide 1 (glp-1) on the differentiation of mesenchymal stem cells from human bone marrow. Am J Physiol Endocrinol Metab.( 2010) 298 : E634-E643

2009

Alvarez, M., Matamoros, T., Menéndez-Arias, L. Increased thermostability and fidelity of DNA synthesis of wild-type and mutant HIV-1 group O reverse transcriptases. J Mol Biol. (2009) 392(4): 872-84

2008

Asúa, T., Bilbao, A., Gorriti, MA., Lopez-Moreno, JA., Del Mar Alvarez, M., Navarro, M., Rodríguez de Fonseca, F., Perez-Castillo, A., Santos, A. Implication of the endocannabinoid system in the locomotor hyperactivity associated with congenital hypothyroidism. Endocrinology (2008) 149(5): 2657-2666

Menéndez-Arias, L., Matamoros, T., Álvarez, M. Ritonavir-boosted darunavir: a powerful option for treatment-experienced HIV-1-infected patients. Future Virol. (2008).3(5)

2005

Santos, A., Del Mar Alvarez, M., Mauro, MS., Abrusci, C., Marquina, D. The transcriptional response of Saccharomyces cerevisiae to Pichia membranifaciens killer toxin.J. Biol Chem. (2005). 280(51): 41881-92.

Álvarez, M., Pérez-Castillo, A., Santos, A. Thyroid hormone regulates Galphai1 gene expression in the rat cerebellar cortex during postnatal development. J Neurochem. (2005) 92(2): 395-404.

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